Generated on 2025-11-19
Hypoxic Burden (HB) quantifies the cumulative oxygen desaturation load during sleep by integrating both the depth and duration of SpO₂ drops. This metric has proven to be a stronger predictor of cardiovascular outcomes than traditional metrics (Azarbarzin et al., AJRCCM, 2019).
Methodology: Sutherland et al. (Sleep, 2022) - HB = Σ (desaturation area below baseline) / total sleep hours
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